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Out-of-equilibrium conformational cycling of GroEL under saturating ATP concentrations
The molecular chaperone GroEL exists in at least two allosteric states, T and R, that interconvert in an ATP-controlled manner. Thermodynamic analysis suggests that the T-state population becomes negligible with increasing ATP concentrations, in conflict with the requirement for conformational cycli...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852005/ https://ncbi.nlm.nih.gov/pubmed/20308583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910246107 |
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