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Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25(+)Foxp3(+) regulatory T cells

Immune-mediated diseases of the CNS, such as multiple sclerosis and its animal model, experimental autoimmune encephalitis (EAE), are characterized by the activation of antigen-presenting cells and the infiltration of autoreactive lymphocytes within the CNS, leading to demyelination, axonal damage,...

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Autors principals: Benkhoucha, Mahdia, Santiago-Raber, Marie-Laure, Schneiter, Gregory, Chofflon, Michel, Funakoshi, Hiroshi, Nakamura, Toshikazu, Lalive, Patrice H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851995/
https://ncbi.nlm.nih.gov/pubmed/20332205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912437107
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