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Hepatocyte growth factor inhibits CNS autoimmunity by inducing tolerogenic dendritic cells and CD25(+)Foxp3(+) regulatory T cells
Immune-mediated diseases of the CNS, such as multiple sclerosis and its animal model, experimental autoimmune encephalitis (EAE), are characterized by the activation of antigen-presenting cells and the infiltration of autoreactive lymphocytes within the CNS, leading to demyelination, axonal damage,...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851995/ https://ncbi.nlm.nih.gov/pubmed/20332205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912437107 |
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