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The neurotrophic hepatocyte growth factor attenuates CD8(+) cytotoxic T-lymphocyte activity
BACKGROUND: Accumulating evidence suggests a deleterious role for CD8(+) T cells in multiple sclerosis (MS) pathogenesis. We have recently reported that hepatocyte growth factor (HGF), a potent neuroprotective factor, limits CD4(+) T cell-mediated autoimmune neuroinflammation by promoting tolerogeni...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881506/ https://ncbi.nlm.nih.gov/pubmed/24344806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-154 |
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