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Water-Soluble Phosphinothiols for Traceless Staudinger Ligation and Integration with Expressed Protein Ligation

The traceless Staudinger ligation is an effective means to synthesize an amide bond between two groups of otherwise orthogonal reactivity: a phosphinothioester and an azide. An important application of the Staudinger ligation is in the ligation of peptides at a variety of residues. Here, we demonstr...

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Hlavní autoři: Tam, Annie, Soellner, Matthew B., Raines, Ronald T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851833/
https://ncbi.nlm.nih.gov/pubmed/17713909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja073204p
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