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Staudinger Ligation of Peptides at Non-Glycyl Residues

The Staudinger ligation provides a means to form an amide bond between a phosphinothioester and azide. This reaction holds promise for the ligation of peptides en route to the total chemical synthesis of proteins. (Diphenylphosphino)methanethiol is the most efficacious of known reagents for mediatin...

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Detalhes bibliográficos
Main Authors: Soellner, Matthew B., Tam, Annie, Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565276/
https://ncbi.nlm.nih.gov/pubmed/17168602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0620056
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