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Staudinger Ligation of Peptides at Non-Glycyl Residues

The Staudinger ligation provides a means to form an amide bond between a phosphinothioester and azide. This reaction holds promise for the ligation of peptides en route to the total chemical synthesis of proteins. (Diphenylphosphino)methanethiol is the most efficacious of known reagents for mediatin...

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Hlavní autoři: Soellner, Matthew B., Tam, Annie, Raines, Ronald T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565276/
https://ncbi.nlm.nih.gov/pubmed/17168602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0620056
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