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The activated state of a sodium channel voltage sensor in a membrane environment

Direct structural insights on the fundamental mechanisms of permeation, selectivity, and gating remain unavailable for the Na(+) and Ca(2+) channel families. Here, we report the spectroscopic structural characterization of the isolated Voltage-Sensor Domain (VSD) of the prokaryotic Na(+) channel NaC...

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Autors principals: Chakrapani, Sudha, Sompornpisut, Pornthep, Intharathep, Pathumwadee, Roux, Benoît, Perozo, Eduardo
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851821/
https://ncbi.nlm.nih.gov/pubmed/20207950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914109107
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