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Structural Refinement of Membrane Proteins by Restrained Molecular Dynamics and Solvent Accessibility Data

We present an approach for incorporating solvent accessibility data from electron paramagnetic resonance experiments in the structural refinement of membrane proteins through restrained molecular dynamics simulations. The restraints have been parameterized from oxygen (ΠO(2)) and nickel-ethylenediam...

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Bibliografske podrobnosti
Main Authors: Sompornpisut, Pornthep, Roux, Benoît, Perozo, Eduardo
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586578/
https://ncbi.nlm.nih.gov/pubmed/18676641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.142984
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