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Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterning
Expression of Sonic Hedgehog (Shh) in the posterior mesenchyme of the developing limb bud regulates patterning and growth of the developing limb by activation of the Hedgehog (Hh) signaling pathway. Through the analysis of Shh and Hh signaling target genes, it has been shown that activation in the l...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851812/ https://ncbi.nlm.nih.gov/pubmed/20212115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912818107 |
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