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FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry

As the smallest and simplest motor enzymes, kinesins have served as the prototype for understanding the relationship between protein structure and mechanochemical function of enzymes in this class. Conventional kinesin (kinesin-1) is a motor enzyme that transports cargo toward the plus end of microt...

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Autori principali: Martin, Douglas S., Fathi, Reza, Mitchison, Timothy J., Gelles, Jeff
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851760/
https://ncbi.nlm.nih.gov/pubmed/20212149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914924107
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