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FRET measurements of kinesin neck orientation reveal a structural basis for processivity and asymmetry

As the smallest and simplest motor enzymes, kinesins have served as the prototype for understanding the relationship between protein structure and mechanochemical function of enzymes in this class. Conventional kinesin (kinesin-1) is a motor enzyme that transports cargo toward the plus end of microt...

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Detalles Bibliográficos
Main Authors: Martin, Douglas S., Fathi, Reza, Mitchison, Timothy J., Gelles, Jeff
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851760/
https://ncbi.nlm.nih.gov/pubmed/20212149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914924107
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