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The P-glycoprotein Inhibitor GF120918 Modulates Ca(2+)-Dependent Processes and Lipid Metabolism in Toxoplasma Gondii

Up-regulation of the membrane-bound efflux pump P-glycoprotein (P-gp) is associated with the phenomenon of multidrug-resistance in pathogenic organisms, including protozoan parasites. In addition, P-gp plays a role in normal physiological processes, however our understanding of these P-gp functions...

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Autors principals: Bottova, Iveta, Sauder, Ursula, Olivieri, Vesna, Hehl, Adrian B., Sonda, Sabrina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851653/
https://ncbi.nlm.nih.gov/pubmed/20386707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010062
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