Host Cell P-glycoprotein Is Essential for Cholesterol Uptake and Replication of Toxoplasma gondii

P-glycoprotein (P-gp) is a membrane-bound efflux pump that actively exports a wide range of compounds from the cell and is associated with the phenomenon of multidrug resistance. However, the role of P-gp in normal physiological processes remains elusive. Using P-gp-deficient fibroblasts, we showed...

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Detalhes bibliográficos
Main Authors: Bottova, Iveta, Hehl, Adrian B., Štefanić, Saša, Fabriàs, Gemma, Casas, Josefina, Schraner, Elisabeth, Pieters, Jean, Sonda, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719384/
https://ncbi.nlm.nih.gov/pubmed/19389707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809420200
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