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The P-glycoprotein Inhibitor GF120918 Modulates Ca(2+)-Dependent Processes and Lipid Metabolism in Toxoplasma Gondii
Up-regulation of the membrane-bound efflux pump P-glycoprotein (P-gp) is associated with the phenomenon of multidrug-resistance in pathogenic organisms, including protozoan parasites. In addition, P-gp plays a role in normal physiological processes, however our understanding of these P-gp functions...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851653/ https://ncbi.nlm.nih.gov/pubmed/20386707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010062 |
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