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Nitrated α-Synuclein Induces the Loss of Dopaminergic Neurons in the Substantia Nigra of Rats

BACKGROUND: The pathology of Parkinson's disease (PD) is characterized by the degeneration of the nigrostriatal dopaminergic pathway, as well as the formation of intraneuronal inclusions known as Lewy bodies and Lewy neurites in the substantia nigra. Accumulations of nitrated α-synuclein are de...

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Main Authors: Yu, Zhongwang, Xu, Xiaohui, Xiang, Zhenghua, Zhou, Jianfeng, Zhang, Zhaohuan, Hu, Chun, He, Cheng
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851648/
https://ncbi.nlm.nih.gov/pubmed/20386702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009956
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