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A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd

Kinesins are microtubule-based motor proteins that power intracellular transport1,2. Most kinesin motors, exemplified by Kinesin-1, move towards the microtubule plus end, and the structural changes that govern this directional preference have been described3–5. By contrast, the nature and timing of...

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Detalhes bibliográficos
Main Authors: Endres, Nicholas F., Yoshioka, Craig, Milligan, Ronald A., Vale, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851630/
https://ncbi.nlm.nih.gov/pubmed/16382238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04320
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