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CD28 and c-Rel-dependent Pathways Initiate Regulatory T Cell Development
Regulatory T cell (Treg) development proceeds via a two step process in which naïve CD4(+) thymocytes are first converted into CD4(+)CD25(+)CD122(+)GITR(+)Foxp3(−) Treg progenitors followed by a second step in which IL2 converts these Treg progenitors into CD4(+)Foxp3(+) Tregs. The costimulatory mol...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851483/ https://ncbi.nlm.nih.gov/pubmed/20228198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903933 |
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