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An autoimmune response to OBP1a is associated with dry eye in the Aire-deficient mouse

Sjögren’s Syndrome is a human autoimmune disease characterized by immune-mediated destruction of the lacrimal and salivary glands. Here, we show that the Aire-deficient mouse represents a new tool to investigate autoimmune dacryoadenitis and keratoconjunctivitis sicca, features of Sjögren’s Syndrome...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DeVoss, Jason J, LeClair, Norbert, Hou, Yafei, Grewal, Navdeep, Johannes, Kellsey, Lu, Wen, Yang, Ting, Meagher, Craig, Fong, Lawrence, Strauss, Erich C., Anderson, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851482/
https://ncbi.nlm.nih.gov/pubmed/20237294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902434
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