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Effector mechanisms of the autoimmune syndrome in the murine model of Autoimmune Polyglandular Syndrome Type 1

Mutations in the Autoimmune regulator (Aire) gene result in a clinical phenomenon known as Autoimmune Polyglandular Syndrome Type I (APS1), which classically manifests as a triad of adrenal insufficiency, hypoparathyroidism, and chronic mucocutaneous infections. In addition to this triad, a number o...

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Detalhes bibliográficos
Main Authors: DeVoss, Jason J., Shum, Anthony K., Johannes, Kellsey P.A., Lu, Wen, Krawisz, Anna K., Wang, Peter, Yang, Ting, LeClair, Norbert P., Austin, Cecilia, Strauss, Erich C., Anderson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556863/
https://ncbi.nlm.nih.gov/pubmed/18768863
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