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Engineering a two-helix bundle protein for folding studies
The SAP domain from the Saccharomyces cerevisiae THO1 protein contains a hydrophobic core and just two α-helices. It could provide a system for studying protein folding that bridges the gap between studies on isolated helices and those on larger protein domains. We have engineered the SAP domain for...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851443/ https://ncbi.nlm.nih.gov/pubmed/20130106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp080 |
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