Combined Oncogenic BRAF Mutation and CDKN2A Inactivation Is Characteristic of a Subset of Pediatric Malignant Astrocytomas

Astrocytomas are the leading cause of solid tumor-related death in children. Progress toward developing effective therapies for these tumors has been modest, in part because of a limited understanding of the genetic alterations responsible for their development. To identify genetic changes that occu...

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Autores principales: Schiffman, Joshua D., Hodgson, J. Graeme, Vandenberg, Scott R., Flaherty, Patrick, Polley, Mei-Yin C., Yu, Mamie, Fisher, Paul G., Rowitch, David H., Ford, James M., Berger, Mitchel S., Ji, Hanlee, Gutmann, David H., James, C. David
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851233/
https://ncbi.nlm.nih.gov/pubmed/20068183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1851
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