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Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
Inappropriate drug delivery, secondary toxicities and persistent chemo- and immuno-resistance have traditionally compromised treatment response in melanoma. Using cellular systems and genetically engineered mouse models, we show that melanoma cells retain an innate ability to recognize cytosolic dsR...
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| Autors principals: | , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851205/ https://ncbi.nlm.nih.gov/pubmed/19647221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.07.004 |
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