Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

The pleiotropic lipid mediator sphingosine-1-phosphate (S1P) can act intracellularly independently of its cell surface receptors through unknown mechanisms. Sphingosine kinase 2 (SphK2), one of the isoenzymes that generates S1P, was associated with histone H3 and produced S1P that regulated histone...

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Main Authors: Hait, Nitai C., Allegood, Jeremy, Maceyka, Michael, Strub, Graham M., Harikumar, Kuzhuvelil B., Singh, Sandeep K., Luo, Cheng, Marmorstein, Ronen, Kordula, Tomasz, Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850596/
https://ncbi.nlm.nih.gov/pubmed/19729656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1176709
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