Cu(i) recognition via cation-π and methionine interactions in CusF

Methionine-rich motifs have an important role in copper trafficking factors, including the CusF protein. Here we show that CusF uses a new metal recognition site wherein Cu(i) is tetragonally displaced from a Met(2)His ligand plane toward a conserved tryptophan. Spectroscopic studies demonstrate tha...

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Bibliografische gegevens
Hoofdauteurs: Xue, Yi, Davis, Anna V, Balakrishnan, Gurusamy, Stasser, Jay P, Staehlin, Benjamin M, Focia, Pamela, Spiro, Thomas G, Penner-Hahn, James E, O’Halloran, Thomas V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850561/
https://ncbi.nlm.nih.gov/pubmed/18157124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.57
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