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Tryptophan Cu(I)–π interaction fine-tunes the metal binding properties of the bacterial metallochaperone CusF

The periplasmic metallochaperone CusF coordinates Cu(I) and Ag(I) through a unique site consisting of a Met(2)His motif as well as a Cu(I)–π interaction between a nearby tryptophan, W44, and the metal ion. Through mutational analyses we investigate here the role that W44 in CusF plays in metal coord...

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Detalhes bibliográficos
Main Authors: Loftin, Isabell R., McEvoy, Megan M., Blackburn, Ninian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808115/
https://ncbi.nlm.nih.gov/pubmed/19381697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-009-0503-y
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