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Modulation of Tramadol Release from a Hydrophobic Matrix: Implications of Formulations and Processing Variables
In the present investigation, hydrogenated cottonseed oil (HCSO) was evaluated as a sustained release matrix for a freely soluble drug, tramadol. Hydrophobic matrix tablets of tramadol, was evaluated by compression of physical mixture of drug and wax, dispersion of drug in HCSO by hot fusion or solu...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850494/ https://ncbi.nlm.nih.gov/pubmed/20300896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9400-5 |
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