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Modulation of Tramadol Release from a Hydrophobic Matrix: Implications of Formulations and Processing Variables

In the present investigation, hydrogenated cottonseed oil (HCSO) was evaluated as a sustained release matrix for a freely soluble drug, tramadol. Hydrophobic matrix tablets of tramadol, was evaluated by compression of physical mixture of drug and wax, dispersion of drug in HCSO by hot fusion or solu...

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Detalhes bibliográficos
Main Authors: Sudha, B. S., Sridhar, B. K., Srinatha, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850494/
https://ncbi.nlm.nih.gov/pubmed/20300896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9400-5
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