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Controlled release formulation of tramadol hydrochloride using hydrophilic and hydrophobic matrix system
The effect of concentration of hydrophilic (hydroxypropyl methylcellulose [HPMC]) and hydrophobic polymers (hydrogenated castor oil [HCO], ethylcellulose) on the release rate of tramadol was studied. Hydrophilic matrix tablets were prepared by wet granulation technique, while hydrophobic (wax) matri...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750624/ https://ncbi.nlm.nih.gov/pubmed/14621963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040331 |
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