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A common intracellular allosteric binding site for antagonists of the CXCR2 receptor

BACKGROUND AND PURPOSE: We have previously shown that SB265610 (1-(2-bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl)-urea) behaves as an allosteric, inverse agonist at the C-X-C chemokine (CXCR)2 receptor. The aim of this study was to determine whether SB265610, in addition to two other known antagon...

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Detaylı Bibliyografya
Asıl Yazarlar: Salchow, K, Bond, ME, Evans, SC, Press, NJ, Charlton, SJ, Hunt, PA, Bradley, ME
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850400/
https://ncbi.nlm.nih.gov/pubmed/20233217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00623.x
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