Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

BICD2 is one of the two mammalian homologues of the Drosophila Bicaudal D, an evolutionarily conserved adaptor between microtubule motors and their cargo that was previously shown to link vesicles and mRNP complexes to the dynein motor. Here, we identified a G2-specific role for BICD2 in the relativ...

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Bibliografski detalji
Glavni autori: Splinter, Daniël, Tanenbaum, Marvin E., Lindqvist, Arne, Jaarsma, Dick, Flotho, Annette, Yu, Ka Lou, Grigoriev, Ilya, Engelsma, Dieuwke, Haasdijk, Elize D., Keijzer, Nanda, Demmers, Jeroen, Fornerod, Maarten, Melchior, Frauke, Hoogenraad, Casper C., Medema, René H., Akhmanova, Anna
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850381/
https://ncbi.nlm.nih.gov/pubmed/20386726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000350
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