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Depletion of tumor-induced regulatory T cells prior to reconstitution rescues enhanced priming of tumor-specific, therapeutic effector T cells in lymphopenic hosts
We reported previously that vaccination of reconstituted-lymphopenic mice resulted in a higher frequency of tumor-specific effector T cells with therapeutic activity than vaccination of normal mice. Here we show that lymphopenic mice reconstituted with spleen cells from tumor-bearing mouse (TBM), a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850261/ https://ncbi.nlm.nih.gov/pubmed/19839008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939453 |
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