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Human Cytochrome P450c17: Single Step Purification and Phosphorylation of Serine 258 by Protein Kinase A
Cytochrome P450c17 (P450c17) is the single microsomal enzyme that catalyzes steroid 17α-hydroxylase and 17,20 lyase activities. The ratio of lyase to hydroxylase activity of human P450c17 determines whether steroidogenesis leads to the synthesis of cortisol or sex steroids. This ratio is regulated p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850244/ https://ncbi.nlm.nih.gov/pubmed/20160131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1247 |
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