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Transforming Growth Factor-β Coordinately Induces Suppressor of Cytokine Signaling 3 and Leukemia Inhibitory Factor to Suppress Osteoclast Apoptosis

Local release of TGF-β during times of high bone turnover leads to elevated levels within the bone microenvironment, and we have shown that TGF-β suppresses osteoclast apoptosis. Therefore, understanding the influences of TGF-β on bone resorbing osteoclasts is critical to the design of therapies to...

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Autors principals: Ruan, Ming, Pederson, Larry, Bradley, Elizabeth W., Bamberger, Ana-Maria, Oursler, Merry Jo
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850239/
https://ncbi.nlm.nih.gov/pubmed/20181800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0813
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