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Increased Food Intake Leads to Obesity and Insulin Resistance in the Tg2576 Alzheimer’s Disease Mouse Model

Recent studies suggest that hyperinsulinemia and insulin resistance are linked to Alzheimer’s disease (AD). In this study, we used Tg2576 transgenic (Tg) mice, a widely used transgenic mouse model for AD, to explore the relationship between increased amyloid β-peptide (Aβ) and insulin resistance. Wh...

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Detalhes bibliográficos
Main Authors: Kohjima, Motoyuki, Sun, Yuxiang, Chan, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850232/
https://ncbi.nlm.nih.gov/pubmed/20176720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1196
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