Absorption, Distribution, Excretion, and Pharmacokinetics of (14)C-Pyronaridine Tetraphosphate in Male and Female Sprague-Dawley Rats

The main objective of this investigation was to determine the absorption, distribution, excretion, and pharmacokinetics of the antimalarial drug pyronaridine tetraphosphate (PNDP) in Sprague-Dawley rats. Following oral administration of a single dose (10 mg/Kg) of (14)C-PNDP, it was observed that th...

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Bibliographic Details
Main Authors: Park, Sang Hyun, Pradeep, Kannampalli
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850153/
https://ncbi.nlm.nih.gov/pubmed/20379367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/590707
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