IFN-β Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3-β

TLR 4 stimulation of innate immune cells induces a MyD88-independent signaling pathway that leads to the production of IFN-β. In this study, we demonstrate glycogen synthase kinase 3-β (GSK3-β) plays a fundamental role in this process. Suppression of GSK3-β activity by either pharmacological inhibit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Huizhi, Garcia, Carlos A., Rehani, Kunal, Cekic, Caglar, Alard, Pascale, Kinane, Denis F., Mitchell, Thomas, Martin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849978/
https://ncbi.nlm.nih.gov/pubmed/18981097
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados