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Reciprocal regulation of TLR2-mediated IFN-β production by SHP2 and Gsk3β
Toll-like receptor 2 (TLR2) mediates the innate immune response to bacterial lipopeptides and peptidoglycans by stimulating the production of inflammatory cytokines. However, the mechanisms by which TLR2 signaling regulates type I interferon (IFN)-β production are poorly understood. Here, we identif...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533723/ https://ncbi.nlm.nih.gov/pubmed/28754897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07316-3 |
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