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Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development
Phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) and myosin binding protein-C (cMyBP-C) by protein kinase A (PKA) independently accelerate the kinetics of force development in ventricular myocardium. However, while MLCK treatment has been shown to increase t...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849963/ https://ncbi.nlm.nih.gov/pubmed/20123786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.183897 |
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