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Loss of Etv5 Decreases Proliferation and RET Levels in Neonatal Mouse Testicular Germ Cells and Causes an Abnormal First Wave of Spermatogenesis
Mice that are ets variant gene 5 (ETV5) null (Etv5(−/−)) undergo the first wave of spermatogenesis but lose all spermatogonial stem cells (SSCs) during this time. The SSC loss in Etv5(−/−) mice begins during the neonatal period, suggesting a role for ETV5 in SSC self-renewal during this period. Here...
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Główni autorzy: | , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
Society for the Study of Reproduction, Inc.
2009
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849825/ https://ncbi.nlm.nih.gov/pubmed/19369650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075200 |
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