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ETV5 is required for continuous spermatogenesis in adult mice and may mediate blood–testes barrier function and testicular immune privilege
The transcription factor Ets-variant gene 5 (ETV5) is essential for spermatogonial stem cell (SSC) self-renewal, as targeted deletion of the Etv5 gene in mice (Etv5(−/−)) results in only the first wave of spermatogenesis. Reciprocal transplants of neonatal germ cells from wild type and Etv5(−/−) tes...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2733827/ https://ncbi.nlm.nih.gov/pubmed/17911411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1411.005 |
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