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Effects of ETV5 (Ets Variant Gene 5) on Testis and Body Growth, Time Course of Spermatogonial Stem Cell Loss, and Fertility in Mice
The transcription factor ets variant gene 5 (ETV5; also known as ERM) is essential for self-renewal of spermatogonial stem cells (SSCs). Mice with targeted disruption of Etv5 (Etv5(−/−)) undergo the first wave of spermatogenesis, but all SSCs are lost during this time, causing a Sertoli cell-only ph...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911230/ https://ncbi.nlm.nih.gov/pubmed/18032421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.107.062935 |
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