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Spermatogonial Stem Cells Derived from Infertile W(v)/W(v) Mice Self-Renew In Vitro and Generate Progeny Following Transplantation
Loss-of-function mutation of the Kit gene causes a severe defect in spermatogenesis that results in infertility due to the inability of its cognate ligand, KIT ligand (KITL), to stimulate spermatogonial proliferation and differentiation. Although self-renewal of mouse spermatogonial stem cells (SSCs...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for the Study of Reproduction, Inc.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849820/ https://ncbi.nlm.nih.gov/pubmed/19369648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.075960 |
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