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Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69

The fidelity of DNA replication is under constant threat from the formation of lesions within the genome. Oxidation of DNA bases leads to the formation of altered DNA bases such as 8-oxo-7,8-dihydroguanine, commonly called 8-oxoG, and 2-hydroxyadenenine, or 2-OHA. In this work we have examined the i...

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Bibliografiska uppgifter
Huvudupphovsmän: Hogg, Matthew, Rudnicki, Jean, Midkiff, John, Reha-Krantz, Linda, Doublié, Sylvie, Wallace, Susan S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849760/
https://ncbi.nlm.nih.gov/pubmed/20166748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901488d
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