Antagonism of CD317 Restriction of Human Immunodeficiency Virus Type 1 (HIV-1) Particle Release and Depletion of CD317 Are Separable Activities of HIV-1 Vpu

Vpu antagonizes human immunodeficiency virus type 1 (HIV-1) particle release inhibition by CD317/BST-2/Tetherin. Whether this Vpu activity strictly requires cellular depletion of the restriction factor is unclear. Here, we characterized CD317 variants with mutations in putative sorting or ubiquitina...

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Main Authors: Goffinet, Christine, Homann, Stefanie, Ambiel, Ina, Tibroni, Nadine, Rupp, Daniel, Keppler, Oliver T., Fackler, Oliver T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849503/
https://ncbi.nlm.nih.gov/pubmed/20147395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01549-09
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