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Direct Evidence from Single-Cell Analysis that Human α-Defensins Block Adenovirus Uncoating To Neutralize Infection

Human α-defensins are evolutionarily conserved effectors of the innate immune response with broadly acting antibacterial activity. Their role in antiviral immunity is less well understood. We previously showed that these antimicrobial peptides are potent inhibitors of human adenovirus infection. Bas...

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Autors principals: Nguyen, Emily K., Nemerow, Glen R., Smith, Jason G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849482/
https://ncbi.nlm.nih.gov/pubmed/20130047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02471-09
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