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Direct Evidence from Single-Cell Analysis that Human α-Defensins Block Adenovirus Uncoating To Neutralize Infection

Human α-defensins are evolutionarily conserved effectors of the innate immune response with broadly acting antibacterial activity. Their role in antiviral immunity is less well understood. We previously showed that these antimicrobial peptides are potent inhibitors of human adenovirus infection. Bas...

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Detalhes bibliográficos
Main Authors: Nguyen, Emily K., Nemerow, Glen R., Smith, Jason G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849482/
https://ncbi.nlm.nih.gov/pubmed/20130047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02471-09
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