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Cadherins and Pak1 Control Contact Inhibition of Proliferation by Pak1-βPIX-GIT Complex-Dependent Regulation of Cell-Matrix Signaling

It is crucial for organ homeostasis that epithelia have effective mechanisms to restrict motility and cell proliferation in order to maintain tissue architecture. On the other hand, epithelial cells need to rapidly and transiently acquire a more mesenchymal phenotype, with high levels of cell motili...

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Bibliographic Details
Main Authors: Liu, Fengming, Jia, Liwei, Thompson-Baine, Ann-Marie, Puglise, Jason M., ter Beest, Martin B. A., Zegers, Mirjam M. P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849475/
https://ncbi.nlm.nih.gov/pubmed/20154149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01247-09
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