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Pak1 and PIX regulate contact inhibition during epithelial wound healing

Wound healing in epithelia requires coordinated cell migration and proliferation regulated by signaling mechanisms that are poorly understood. Here we show that epithelial cells expressing constitutively active or kinase-dead mutants of the Rac/Cdc42 effector Pak1 fail to undergo growth arrest upon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zegers, Mirjam M.P., Forget, Marie-Annick, Chernoff, Jonathan, Mostov, Keith E., ter Beest, Martin B.A., Hansen, Steen H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC175788/
https://ncbi.nlm.nih.gov/pubmed/12912914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg398
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