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Pak1 and PIX regulate contact inhibition during epithelial wound healing

Wound healing in epithelia requires coordinated cell migration and proliferation regulated by signaling mechanisms that are poorly understood. Here we show that epithelial cells expressing constitutively active or kinase-dead mutants of the Rac/Cdc42 effector Pak1 fail to undergo growth arrest upon...

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Detalhes bibliográficos
Main Authors: Zegers, Mirjam M.P., Forget, Marie-Annick, Chernoff, Jonathan, Mostov, Keith E., ter Beest, Martin B.A., Hansen, Steen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC175788/
https://ncbi.nlm.nih.gov/pubmed/12912914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg398
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