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Pak1 and PIX regulate contact inhibition during epithelial wound healing

Wound healing in epithelia requires coordinated cell migration and proliferation regulated by signaling mechanisms that are poorly understood. Here we show that epithelial cells expressing constitutively active or kinase-dead mutants of the Rac/Cdc42 effector Pak1 fail to undergo growth arrest upon...

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Udgivet i:EMBO J
Principais autores: Zegers, Mirjam M.P., Forget, Marie-Annick, Chernoff, Jonathan, Mostov, Keith E., ter Beest, Martin B.A., Hansen, Steen H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg398
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