Initial T cell frequency dictates memory CD8(+) T cell lineage commitment

Memory T cells can be divided into central memory T cell (T(CM) cell) and effector memory T cell (T(EM) cell) subsets based on homing characteristics and effector functions. Whether T(EM) and T(CM) cells represent interconnected or distinct lineages is unclear, although the present paradigm suggests...

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Bibliographic Details
Main Authors: Marzo, Amanda L, Klonowski, Kimberly D, Le Bon, Agnes, Borrow, Persephone, Tough, David F, Lefrançois, Leo
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849311/
https://ncbi.nlm.nih.gov/pubmed/16025119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1227
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